A 66-year-old man with a history of atherosclerosis, hemodialysis, and 45+ years of cigarette smoking (one pack a day) presented to the doctor with a sudden onset of lower abdominal pain and cramping, gastrointestinal bleeding, and diarrhea that occurred within the last 24 hours. Laboratory testing confirmed heme-positive stool. Cryptitis with “withering” crypts were visible on histopathologic testing. The patient was not on any medications and had no previous history of gastrointestinal disease.
Which diagnosis is it?
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