Poikiloderma of Civatte is a chronic, benign skin condition caused by long-term sun exposure in adults with lighter skin phototypes. It affects women more frequently than men and typically appears in and after the fifth decade of life. It presents as mottled erythema involving the lateral neck and the superior medial chest. Telangiectasias, hyper- and/or hypopigmentation, and superficial (epidermal or superficial dermal) atrophy may also be seen.

Poikiloderma of Civatte develops slowly over months to years. As many as half of all patients may complain of mild itching, burning, or flushing in affected areas. Contact sensitization to chemicals present in fragrances and cosmetics has been proposed as a cofactor in the development of this disorder.