Metabolic dysfunction-associated steatotic liver disease
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Synopsis
![Metabolic dysfunction-associated steatotic liver disease : Fatigue, Hepatomegaly, Alkaline phosphatase elevated, ALT elevated, AST elevated, Malaise, RUQ pain](/visualdx/sympticonswm/2225.png?r=1fdb69a28)
Screening for MASLD is of the utmost importance in patients with underlying risk factors, primarily obesity and metabolic syndrome, as it is often asymptomatic. Some patients report vague symptoms such as fatigue or mild right upper quadrant abdominal pain. If MASLD progresses to cirrhosis, patients will often present with signs and symptoms of advanced liver disease: spider angiomata, gynecomastia, ascites, jaundice, and peripheral edema.
The primary risk factors for MASLD are central obesity, type 2 diabetes mellitus, and hyperlipidemia. Modification of these risk factors, mostly through weight loss and dietary and lifestyle changes, is the most effective preventive and treatment strategy.
Codes
K76.0 – Fatty (change of) liver, not elsewhere classified
SNOMEDCT:
1231824009 – Non-alcoholic fatty liver disease
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Last Updated:11/30/2023