Löfgren syndrome
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Synopsis
Löfgren syndrome is a constellation of symptoms that is nearly always suggestive of acute sarcoidosis. The primary symptoms are erythema nodosum and hilar lymphadenopathy. Arthritis, uveitis, and fever also frequently occur. Primary tuberculosis can rarely present with hilar lymphadenopathy and erythema nodosum. The simultaneous presence of all the typical features of Löfgren syndrome, however, is highly specific for sarcoidosis.
Löfgren syndrome predominantly occurs in female patients of Northern European descent. Unlike other manifestations of sarcoidosis, Löfgren syndrome usually resolves within 2 years and rarely relapses. NSAIDs are the typical treatment, with immunosuppression sometimes required.
Löfgren syndrome predominantly occurs in female patients of Northern European descent. Unlike other manifestations of sarcoidosis, Löfgren syndrome usually resolves within 2 years and rarely relapses. NSAIDs are the typical treatment, with immunosuppression sometimes required.
Codes
ICD10CM:
D86.86 – Sarcoid arthropathy
SNOMEDCT:
238676008 – Lofgrens syndrome
D86.86 – Sarcoid arthropathy
SNOMEDCT:
238676008 – Lofgrens syndrome
Differential Diagnosis & Pitfalls
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Last Updated:10/25/2015