Atrophoderma vermiculatum (AV), also known as folliculitis ulerythematosa reticulata, is a rare variant of keratosis pilaris atrophicans. Patients with this follicular dermatosis typically present in childhood with a reticular pattern of atrophic pits on the cheeks, preauricular region, and forehead. The condition progresses gradually. AV is sporadic in most cases, but there have been reports of autosomal dominant inheritance.

In a review of 25 cases of AV, the mean age of onset was 10 years, with ages ranging from 3 months to 25 years. One case of congenital AV was noted. Males represented 63% of all cases that were reviewed.

The exact etiology of AV is unknown. One hypothesis is that keratinocytes mediate release of inflammatory cytokines such as transforming growth factor beta (TGF-β) in response to follicular plug formation. This process can result in fibrosis and the characteristic "honeycomb" atrophic lesions seen in AV.

AV is known to occur both as an isolated skin condition and in association with certain genetic disorders. AV has been reported in association with Down syndrome, Ehlers-Danlos syndrome, Marfan syndrome, Melkersson-Rosenthal syndrome, Rombo syndrome, neurofibromatosis, TGFBR2-related Loeys-Dietz syndrome, congenital heart block and atrial septal defect with Eisenmenger complex, and unilateral AV with ipsilateral congenital cataract.