Chemotherapy-induced mucositis in Adult
See also in: Oral Mucosal LesionAlerts and Notices
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Synopsis
While not all chemotherapeutic agents will cause mucositis, many of them have this capability. Some agents (eg, methotrexate and etoposide) are excreted in saliva, which increases their toxicity. The degree to which mucositis is induced is also dependent on the drug and the age of the patient, with younger patients often experiencing more severe signs and symptoms. Chemotherapy-induced mucositis tends to be less severe in patients who have received recombinant human granulocyte colony-stimulating factor (G-CSF). Patients complain of pain and burning that is exacerbated by eating and by oral hygiene procedures.
Oral mucositis combined with gastrointestinal mucositis may occur in about 8% of patients who receive standard-dose chemotherapy with subsequent development of myelosuppression. Suggestive symptoms include pain, nausea / vomiting, and diarrhea.
Related topic: drug-induced oral mucositis
Codes
K12.31 – Oral mucositis (ulcerative) due to antineoplastic therapy
SNOMEDCT:
403666006 – Drug-induced mucositis
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Last Updated:07/18/2024