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Drug-induced cough
Other Resources UpToDate PubMed

Drug-induced cough

Contributors: Abhijeet Waghray MD, Paritosh Prasad MD
Other Resources UpToDate PubMed

Synopsis

A variety of medications can induce cough through different mechanisms.

The most common class of medications causing cough is the angiotensin converting enzyme (ACE) inhibitors, which decrease bradykinin metabolism and are thought to cause 75% of cases of drug-induced cough.

Other medications induce cough by provoking bronchospasm (including beta blockers, NSAIDs, and aspirin-containing products) or by worsening gastroesophageal or laryngopharyngeal reflux (including bisphosphonates, calcium antagonists, and systemic steroids).

Other mechanisms of drug-induced cough are idiopathic and/or can herald the onset of interstitial lung disease or other disorders.

Codes

ICD10CM:
J70.4 – Drug-induced interstitial lung disorders, unspecified
R05.9 – Cough, unspecified

SNOMEDCT:
196051003 – Drug-induced interstitial lung disorders
49727002 – Cough

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Diagnostic Pearls

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Differential Diagnosis & Pitfalls

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Best Tests

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Management Pearls

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Therapy

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Drug Reaction Data

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References

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Last Reviewed:02/20/2018
Last Updated:02/20/2018
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Drug-induced cough
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A medical illustration showing key findings of Drug-induced cough : Cough
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