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Enchondroma in Adult
Other Resources UpToDate PubMed

Enchondroma in Adult

Contributors: Brianna Caraet MD, David Sullo MD, Susan M. McDowell MD
Other Resources UpToDate PubMed

Synopsis

Causes / typical injury mechanism: Enchondroma is a benign, hyaline-cartilage producing tumor located in the medullary canal of the diaphysis or metaphysis of long bones.

Ollier disease and Maffucci syndrome are nonhereditary conditions that present as multiple enchondromas. Ollier disease involves multiple asymmetric enchondromas of the digits. It is most commonly seen in childhood. These slow-growing tumors usually stop growing after puberty, but masses can create deformity and limb asymmetry. Pathologic fractures may be seen. Ollier disease has a 15%-20% risk for secondary chondrosarcoma.

Classic history and presentation: The proximal phalanx is the typical location. These tumors are also common incidental findings in the distal femur, proximal humerus, and tibia. Mean length is usually less than 5 cm.

Solitary enchondroma itself has about a 1% risk of malignant transformation into chondrosarcoma. It is important to distinguish enchondroma from chondrosarcoma, a malignant tumor. Patients with chondrosarcoma of the extremity are more likely to present with nighttime pain, pathologic fracture, endosteal cortical scalloping, bony reactive changes, and larger lesions (> 6 cm). Assume any pelvic cartilage tumor in an adult is a chondrosarcoma until proven otherwise. Rib and scapula lesions are also more likely to be chondrosarcomas.

Prevalence: Enchondroma is a latent lesion that comprises 15%-25% of cartilage tumors. It is the most common hand tumor, accounting for 90% of cases. Enchondroma usually presents in the third and fourth decades of life and occurs equally between both sexes.

Pathophysiology: Enchondroma pathophysiology is believed to involve incomplete endochondral ossification in which physeal remnants become entrapped in the medullary cavity of the metaphysis and proliferate. In the hand, enchondromas are typically diagnosed after a pathologic fracture. Elsewhere, they are typically an asymptomatic incidental finding on x-ray or advanced imaging performed for other reasons. Pain is usually due to a nearby abnormality rather than the tumor itself.

Codes

ICD10CM:
D16.10 – Benign neoplasm of short bones of unspecified upper limb

SNOMEDCT:
423699002 – Enchondroma

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Last Reviewed:08/12/2020
Last Updated:04/14/2024
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Enchondroma in Adult
Imaging Studies image of Enchondroma - imageId=7900659. Click to open in gallery.  caption: '<span>Multiple enchondromas scattered throughout the 4th and 5th fingers.</span>'
Multiple enchondromas scattered throughout the 4th and 5th fingers.
Copyright © 2024 VisualDx®. All rights reserved.